The QFT-Plus assay has 2 distinct TB antigen tubes: TB Antigen Tube 1 (TB1) and TB Antigen Tube 2 (TB2). Both tubes contain peptide antigens from ESAT-6 and CFP-10 for stimulation of a CD4+ T-cell IFN-gamma response.

Två innehåller M. tuberculosis-specifika peptidantigener (TB1 TB2), ett innehåller kontrollmitogen (Mitogen) och ett innehåller inga stimulanter (Nil). Laboratoriet betraktar resultatet av IGRA-testet som positivt om resultatet av TB1 eller TB2 är

The following procedures should be followed for optimal results: 1. Label tubes appropriately. Make sure each tube (Nil, TB1, TB2, and Mitogen… A 1 mL blood sample collected from enrolled TB patients and low-risk individuals was dispensed into each tube (TB1 and TB2 tubes of QFT-Plus assay, and nil, mitogen, antigen tubes of QFT-GIT assay). Nil (IU/ml) TB1 minus Nil (IU/ml) TB2 minus Nil (IU/ml) Mitogen minus Nil (IU/ml) QFT -Plus Result Re sult interpretation ≤8.0 ≥0.35 and ≥25% of Nil Any Any Positive M. tuberculosis infection likely Any ≥0.35 and ≥ 25% of Nil <0.35 or ≥0.35 and <25% of Nil <0.35 or ≥0.35 and <25% of Nil 1. NIL (grå kork) negativ kontroll 2. TB1 antigen (grön kork) 3. TB2 antigen (gul kork) 4.

2019-01-17 · infection is actually recent or active. The greater the difference between TB2 and TB1 (reflecting activated CD8 cells), the more likely this is possible. Be careful – look at control values (nil and mitogen) first to be sure test is interpretable , then look at TB1 and TB2 tubes 1 mL into each of 4 (Nil, TB1, TB2 and Mitogen) QFT-Plus Blood Collection Tubes. Unacceptable Conditions. Improperly filled tubes, frozen or centrifuged specimens.

1 mL into each of 4 (Nil, TB1, TB2 and Mitogen) QFT-Plus Blood Collection Tubes.

22 Jan 2020 4 h: a Nil tube, TB tube, and a Mitogen tube for QFT-GIT or Nil tube, TB1 tube, TB2 tube, and. 120. Mitogen tube for GFT-Plus. The Mitogen tube

0.01. IU/mL. The Nil tube value reflects the background interferon Lower than expected results with the Mitogen tube prevent false-negative The TB1 Antigen tube is coated with the The TB2 Antigen tube is coated with t Custom QFT-Plus tubes: – Nil – same grey color. – TB1 – green, CD4 only.

(Mitogen), eine Negativkontrolle (Nil) und zwei eigentliche Tbc-Teströhrchen (TB1 und TB2). Die Antigene in den Tbc-Teströhrchen TB1 und TB2 (u.a. ESAT-6 und CFP-10) stimulieren die Ausschüttung von IFN-γ durch T-Lymphozyten, sofern der Patient bereits früher in seinem Leben Kontakt zu M. tuberculosis Komplex hatte.

QuantiFERON MITOGEN minus NIL, No reference interval.

Nil (IU/ml) TB1 minus Nil (IU/ml) TB2 minus Nil (IU/ml) Mitogen minus Nil (IU/ml) QFT -Plus Result Re sult interpretation ≤8.0 ≥0.35 and ≥25% of Nil Any Any Positive M. tuberculosis infection likely Any ≥0.35 and ≥ 25% of Nil <0.35 or ≥0.35 and <25% of Nil <0.35 or ≥0.35 and <25% of Nil 1. NIL (grå kork) negativ kontroll 2. TB1 antigen (grön kork) 3. TB2 antigen (gul kork) 4. Mitogen (lila kork) positiv kontroll. Direkt efter provtagningen. Skaka rören för hand.
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Sample must be delivered to the lab no more than 8 hours after collection.

Direkt efter provtagningen.
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1 May 2018 TB1 minus Nil. (IU/mL). TB2 minus Nil. (IU/mL). Mitogen minus Nil. (IU/mL)*. QFT- PLUS Result. Report/Interpretation. ≤8.0. ≥0.35 and. ≥ 25%.

2019-11-27 · Nil TB Response Interpretation Positive <=8.0 TB1 and/or TB2 minus Nil M. tuberculosis >=0.35 and >=25% of Nil infection is A test is considered positive for interferon-gamma response to the TB1 and TB2 Antigen tubes that are significantly above the NIL value. The NIL sample adjusts for background, heterophile antibody effects, or non-specific interferon-gamma in blood samples. 2021-4-13 · TB1-NIL: IU/mL: 6408A-7: Mycobacterium tuberculosis stimulated gamma interferon corrected for background: 86023524: TB2-NIL: IU/mL: 64084-7: Mycobacterium tuberculosis tuberculin stimulated gamma interferon/Mitogen stimulated gamma interferon: Rely on accurate, efﬁcient, and objective TB detection. 2019-6-24 · Ensure each tube (Nil, TB1, TB2 and Mitogen) is identifiable by its label or other means once the cap is removed. It is recommended to transfer the recorded time and date of blood collection from the lithium-heparin tubes to the QFT-Plus Blood Collection Tubes. b) Samples must be evenly mixed by gentle inversion before dispensing into QFT-Plus 62873 NIL: 62874 MITOGEN-NIL: 62875 TB1-NIL: 62876 TB2-NIL: Test Version.