CD137, also called 4-1BB, is a member of the TNF receptor superfamily with T-cell costimulatory functions (5). Signaling through CD137 by its natural ligand, CD137L, or agonistic antibody promotes the expansion of T cells, sustains their survival, and enhances their cytolytic effector functions.

CD Markers - CD13. Granulocytes (most, but low levels in newbornss, Mod Pathol 1993;6:414), interdigitating dendritic cells, large granular lymphocytes (some), macrophages, mast cells, monocytes, myelomonocytes and osteoclasts

CD163 is a protein that in humans is encoded by the CD163 gene. CD163 is the high affinity scavenger receptor for the hemoglobin-haptoglobin complex and in the absence of haptoglobin - with lower affinity - for hemoglobin alone. It also is a marker of cells from the monocyte/macrophage lineage. CD163 functions as innate immune sensor for gram-positive and gram-negative bacteria. The receptor was discovered in 1987. 2013-10-26 · are marked by expressing CD137, a T cell costimulatory receptor. In this issue of Clinical Cancer Research, Ye and colleagues utilize CD137 as a marker to successfully enrich and expand tumor-specific T cells from cancer tissues for adaptive immunotherapy (1).

It is of interest to immunologists as a co-stimulatory immune checkpoint molecule. The murine beige adipocyte marker CD137 is present on some human WAT ASCs. Importantly, the expression of CD137 appears to be associated with the cell’s capacity for induction of UCP1 expression. This indicates that CD137 may also be a marker for beige APCs in humans. CD137, also called 4-1BB, is a member of the TNF receptor superfamily with T-cell costimulatory functions (5).

Märker dock att mycket duktiga personer som tidigare både skrivit och svarat försvunnit. Så forumet markers / [Dimitri Guala. - Stockholm : NBC defence, Swedish CXCL16 and CD137 in atherosclerosis / Dick Wågsäter.

Natural Killer NK Cell Marker (CD3, NCAM1, CD94, NKG2D, SLAMF6, NK-p44) Antibody Panel - Human Antibody panels datasheet (ab254014). Abcam offers quality products including antibodies, assays and…

| 中国 CD137, ligand signaling is independent of the presence of CD137 [20]. CD137 ligand signaling also enhances monocyte migration in vitro and in vivo. Immobilized rCD137 protein induced the movement of peripheral human monocytes in vitro [26]. Fur-ther, 6 times as many monocytes inﬁltrated CD137-express-ing cell spheroids than control spheroids.

欢迎来到肿瘤免疫学院，上期内容全方位盘点了免疫治疗的抑制和活化通路，如slamf7通路，cd137，gitr,ox40共刺激信号通路以及ctla-4，pd-1，lag-3和tigit共抑制信号通路等，下面一分钟快速了解本期io秒懂系列视频--cd137如何触发先天性免疫和适应性免疫？

2019-11-08 · CD137 was originally discovered in 1989 and reported as a cell surface protein mainly located on activated T cells .

This panel contains 5 recombinant rabbit monoclonal antibodies against CD137, a member of the tumor necrosis factor receptor family, provides expansion and survival signal to T cells.
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CD163 functions as innate immune sensor for gram-positive and gram-negative bacteria.

Therefore, CD137 can be a useful biomarker and an important tool for the selection of tumor-reactive T cells.
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CXCL16 and CD137 in atherosclerosis. Author : Dick Wågsäter; Allan Sirsjö; Ewa Ehrenborg; Örebro universitet; [] Keywords : MEDICAL AND HEALTH

CD137 also increases the inﬁltration of effector T(T eff 2015-06-01 CD137 is a costimulatory receptor belonging to the TNF receptor superfamily and is almost uniformly expressed by activated CD4 + and CD8 + T cells as well as some APCs. 32 The inducible expression of CD137 in T cells upon activation has recently been used as a positive selection marker for immunomagnetic column selection for ex vivo expansion of antigen‐specific T cells. 33, 34 The time to maximal CD137 … CD137, ligand signaling is independent of the presence of CD137 [20].